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BindusChem - Highlights

IP Generation

Chemical Development and Scaleup

Patentable Work

The very first project led to patent application by The Hamner Institute 

 WO2015009882A2 

Patentable Work

Chemical Development and Scaleup

Patentable Work

A highly hydrophobic natural product and similar analogs made into water soluble for further development

Chemical Development and Scaleup

Chemical Development and Scaleup

Chemical Development and Scaleup

Chemical development and scale up of  a clinical candidate involving 12 steps

GABA Inhibitors

CB1 and CB2 inhibitors

Chemical Development and Scaleup

  • Make 10 compounds and screen for the target 
  • Lead optimization and a clinical candidate within 100 molecules.

CB1 and CB2 inhibitors

CB1 and CB2 inhibitors

CB1 and CB2 inhibitors

  • Non-natural, highly potent (based on similar molecules)
  • Tune the selectivity between CB1 and CB2 by easy modifications 
  • need less than 50 molecules for potential candidate

SERMs

CB1 and CB2 inhibitors

CB1 and CB2 inhibitors

  • This is ever changing because of sub-types and drug resistance. 
  • For new scaffolds and new molecules, worth to spend our skills
  • If you are interested in any of our work, please contact us tbala@binduschem.com

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